The active ingredients in Nativo, tebuconazole and trifloxystrobin, work in different ways to control fungal infections in crops. Tebuconazole is a demethylase inhibitor that disrupts the structure of the fungal cell wall, preventing the fungus from reproducing and growing. Trifloxystrobin interferes with the respiration process in plant pathogenic fungi. According to the Fungicide Resistance Action Committee (FRAC), tebuconazole is classified as group 3 and trifloxystrobin is classified as group 1. This classification system is used to help identify the potential for the development of resistance to fungicides.